April 2024: New paper out of our collaborators in the Ellis group in Toronto, Canada. A nice story using our hiPSC-derived astrocyte protocol to study astrocyte release of extracellular vesicles and their miRNA cargo that can influence neuronal gene expression. Thanks for the nice collaboration!
March 2024: Very good news that the NWO Gravitation grant was awarded to the iCNS project, a large national consortium coordinated by Inge Huitinga at the Brainbank/Netherlands Institute for Neuroscience in Amsterdam. Our lab will contribute stem cell modelling to validate findings in living human brain cells. The project will combine many disciplines such as the development of a ‘brain atlas’ of psychiatric symptoms based on patient post mortem material and novel technologies in chemistry, transcriptomics, microscopy and molecular biology. Very exciting!
February 2024: The 3D-BrAIn project is nicely coming along, read more about it on the dedicated website.
February 2024: Pablo Sprunken started his BSc internship in our lab from the Avans Hogeschool in Breda. Welcome Pablo!
January 2024: Two New Years party’s, one at our department of Psychiatry (ApresPsy) and a pot luck dinner that resulted in some awesome dishes with all the different nationalities in our group!
December 2023: Not all news is happy. We are sad to see Sophie leave the lab, we wish her all the best in health and luck and hope to see her back soon!
December 2023: Sinterklaas lab party!
November 2023: María Madejon Sanchez and Deniz Gülyurt will start their Erasmus MC Neuroscience Master internships in our lab. Also Michell Forgione will start her internship for the Neuroscience and Cognition Master program Utrecht.
This visit was also in the context of the Horizon Europe SAME-NeuroID project and a nice opportunity to present our work, visit the labs at PORT Lukasiewicz and the beautiful city of Wroclaw. Thanks to the organizers for a great conference!
September 2023: Willemijn Hoogenberg started her internship in our lab from the BML program at Hogeschool Rotterdam.
Welcome Willemijn!
August 2023: Maurits gave a great talk on scRNA analysis of human astrocytes at the ACE SCORE day at the Bibliohtheektheater in Rotterdam August 31st.
July 2023: Juliette was awarded an ENW-XS Grant from NWO! An interesting project bridging her expertise in DNA repair from her PhD work and her current work on human stem cell-derived neurons. How does DNA-repair work in post-mitotic neurons? The award received a lot of attention online at Amazing Erasmus MC and OPEN Rotterdam. Well deserved, congratulations Juliette!
July 2023: Lab outing, games and boat BBQ! Also saying ‘goodbye’ to Esmée, Nikki and Carlos who did a fantastic job in their master internships in our lab. Good luck on next adventures!
July 2023: Euro Glia meeting in Berlin. Great meeting, catching up with a lot of people and excellent poster by Sakshi presenting work on microglia in our Create2Solve project.
June 2023: Erasmus MC Picnic
June 2023: Kick-off meeting for the 3D-BrAIn project, finally meeting in person!
April 2023: Official start of the 3D-BrAIn project! Check out the new website and logo designed by Catalyze.
March 2023: Review paper out in Neuroscience Applied on guidelines for using hiPSCs to model neuropsychiatric disorders
Collaborative paper with a large group of hiPSC modelling labs
March 2023: Femke, Juliette and Hilde presented at the annual NVvP meeting (Nederlandse Vereniging voor Psychiatrie).
February 2023: Julia Christiaanse started her internship in our lab for her BSc Bioinformatics at Hogeschool Leiden.
Welcome Julia!
January 2023: Paper out in Cell Reports on improving precise gene editing
Collaboration with the Tijsterman group, Juliette performed validation experiments to improve precise CRISPR/Cas9 HDR editing in human iPSCs. The paper was also covered by the Dutch newspaper NRC.
January 2023: Carlos Jiménez Gonzáles starts his internship in our lab for his MSc Neurobiology at Radboud UMC Nijmegen
Welcome Carlos!
January 2023 Late Sinterklaas lab party
December 2022: Rubicon grant for Bas Lendemeijer
Bas received Rubicon funding to start as a postdoc at Columbia University in New York. Congratulations Bas!
December 2022 EU Pathfinder funding for 3D BrAIn project
We are very excited to start a new project in April 2023 together with Alessandro Maccione from 3Brain, Silvia Cappello from LMU in Munich, Michele Piana and Cristina Campi from University of Genua. With help from Catalyze.
November 2022: Sitara Chakrasali starts her internship in our lab for her MSc Neuroscience at Erasmus MC
Welcome Sitara!
October 2022: Nikki Kolsters starts her internship in our lab for her MSc Neurobiology at Radboud UMC Nijmegen
Welcome Nikki!
November 2022: Sophie Cohen starts as a PhD student in our lab
Sophie has an MSc Neuroscience background and will work on hiPSC models for schizophrenia. Welcome Sophie!
June 2022 Lab Outing at Mooie Boules and lab BBQ
May 2022 Create2Solve 3D-MICro Brain meeting
We received 5year funding from the MKMD ZonMw Create2Solve program for a project to create reproducible small scale brain model cultures with all major brain cell types in cortical adherent organoids, including myelinating oligodendrocytes and microglia. The resulting 3D MICro-brain model (3D Myelination and Inflammation Cortical Organoids) can be used for phenotype and therapeutic screening. We work together with industry for this project, including Core Life Analytics for advanced image analysis software. We had a great first in person meeting in Rotterdam.
De Vrij lab 